植物乳杆菌N56-12菌株 BioVector NTCC质粒载体菌种细胞基因保藏中心

植物乳杆菌N56-12菌株 BioVector NTCC质粒载体菌种细胞基因保藏中心 Lactobacillus plantarum N56-12
Cat #: NTCC596289
Deposited As Lactobacillus arabinosus N56-12
Strain Designations N56-12
Application In order to investigate changes in platycosides, as well as antimicrobial activities of bronchus diseases-inducing bacteria (Corynebacterium diphtheriae, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes) of Platycodon grandiflorum root (PGR) fermented by lactic acid bacteria
Biosafety Level 1
Type Strain no
Comments In order to investigate changes in platycosides, as well as antimicrobial activities of bronchus diseases-inducing bacteria (Corynebacterium diphtheriae, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes) of Platycodon grandiflorum root (PGR) fermented by lactic acid bacteria (Leuconostoc mesenteroides N12-4, Leuc. mesenteroides N58-5, Lactobacillus plantarum N76-10, L. plantarum N56-12, Lactobacillus brevis N70-9, and L. brevis E3-8). Growth of L. plantarum on PGR was most active during lactic acid fermentation using different strains. Total platycoside, platycoside E, platycodin A, polygalacin D2, polygalacin D, and diapioplatycoside E contents of PGR fermented for 96 h at 37°C by Leuc. mesenteroides and L. plantarum increased, whereas contents of platycodin D and platycodin D3 were reduced. The antimicrobial activity on PGR fermented by L. plantarum N56-12 exhibited strong microbial proliferation for all four kinds of bronchus disease-inducing bacteria and was higher than that of non-fermented PGR extract. MIC of fermented PGR extract by L. plantarum N56-12 on C. diphtheriae, K. pneumoniae, S. aureus, and S. pyogenes were 45, 10, 50, and 25 mg/mL, respectively. Thus, this result shows that the antimicrobial activities of bronchus disease-inducing bacteria and platycoside content of PGR by L. plantarum N56-12 were higher than that of non-fermented PGR extract.
Medium Lactobacilli MRS Agar/Broth
Growth Conditions
Temperature: 37°C
Atmosphere: 5% CO2


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